Nobody signs up for suffering, unless that are that spooky performance art woman who's name elludes me, but it comes knocking to the door of almost everyone eventually, in some form.
Pretty much everybody of my generation is aware than heroin use, for example, can often be a path to great suffering, having seen "Trainspotting" and other such films, and yet people still try it, with some able to stop it or control their use and others not.
A well-known Australian musician used on it on occasion, didn't inject, and kept his use under control. He befriended another local musician who he introduced to it, thinking he could use it in the same controlled manner. Possibly because he had more money to buy it his friend soon became addicted, an addiction than lasted 10 years and cost him his marriage, his children, his friendships, his house, his money, but strangely not his career.
He tried rehab many times with no success.
He ended up moving from Australia and living in Sweden (nearer to his estranged family) in a house of junkies.
Eventually he said the drug gave him up, by no longer working for him. It wasn't his willpower, he said. You could say he was blessed.
Than was some years ago.
Now he is a healthy 60+ year old currently touring the world with his active and recording band.
After his addiction he had 3 more children to two women, to bring his family to a total of 5 girls, including 2 lots of twins. 2 are adults now with successful lives and 3 are possibly teenagers, who he cares for alone, I believe.
Below he speaks a bit about his experience.
On a final note, his friend who introduced him to heroin and whose friendship was lost because of it, died young at 48, of a reported heart attack, blamed by friends on his excessive alcohol use.
Poison comes in many forms...
https://youtu.be/uPAt-bb85jo